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The EPCS 2.0 Act requires group health plans and health insurance issuers to establish policies mandating that participating providers electronically transmit prescriptions for Schedule II–V controlled substances beginning January 1, 2026. The bill specifies technical standards for e-prescribing, allows for limited exceptions (such as technological failures, economic hardship, or when electronic prescribing would delay necessary treatment), and prohibits plans and issuers from rejecting claims based on prescription format or requiring specific e-prescribing vendors. Plans and issuers must annually attest compliance to federal agencies.
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