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The Pharmaceutical Supply Chain Defense and Enhancement Act directs the Secretary of Health and Human Services to identify critical drugs essential to public health and national security, and to enter into contracts with U.S.-based manufacturers to increase domestic production capacity for these drugs and their active pharmaceutical ingredients. The bill authorizes $5 billion for manufacturing contracts (2025–2029) and $4 billion for federal procurement of domestically manufactured drugs (2029–2033), with requirements that contractors maintain supply chain redundancy, 3-month inventories, and fair pricing, while also establishing transparency reporting requirements for domestic suppliers to federal programs.
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